The event takes place in the Italian city’s Parco San Giuliano between 12th and 14th July.
Editors, Mura Masa, Young Thug and LP are also among the acts appearing across the weekend.
Tickets to Home Festival are on sale now.
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The track features on last month’s ‘Back In Love City’.
A decade into the game, The Vaccines are rallying together stronger than ever as they journey through the fictional terrains of Love City…
Their new album ‘Back In Love City’ arrives on Friday.
It feels like the purest Vaccines album yet.